Publications

2026

1. R-package agentBayes: likelihood-based statistical methods for agent-based models

   Niklas Moser, Dmitri Finkelshtein, Georgy Chargaziya, Stephen Cornell, Sara Hamis, Jacob Scott, Dagim S. Tadele, and Otso Ovaskainen

   PLOS Computational Biology, 2026
2. Physics-Informed Neural Networks for Biological 2D+t Reaction-Diffusion Systems

   William Lavery, Jodie A Cochrane, Christian Olesen, Dagim Shiferaw Tadele, John T Nardini, and Sara Hamis

   arXiv preprint arXiv:2604.18548, 2026

2025

1. Decoding cancer evolution through adaptive fitness landscapes

   Rowan Barker-Clarke, Eshan S King, Jeff Maltas, J Arvid Ågren, Dagim Shiferaw Tadele, and Jacob G Scott

   Cancer Systems Biology: Translational Mathematical Oncology, 2025
2. The balance between intrinsic and ecological fitness reveals hidden regimes in eco-evolutionary population dynamics

   Rowan J Barker-Clarke, Jason M Gray, Sydney Leither, Maximilian AR Strobl, Jeff Maltas, Dagim Shiferaw Tadele, Michael Hinczewski, and Jacob G Scott

   Preprint: Research Square, 2025

2024

1. Diverse mutant selection windows shape spatial heterogeneity in evolving populations

   Eshan S King, Dagim S. Tadele, Beck Pierce, Michael Hinczewski, and Jacob G Scott

   PLOS Computational Biology, 2024
2. Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data

   Chenyu Wu, Einar Bjarki Gunnarsson, Even Moa Myklebust, Alvaro Köhn-Luque, Dagim Shiferaw Tadele, Jorrit Martijn Enserink, Arnoldo Frigessi, Jasmine Foo, and Kevin Leder

   PLOS Computational Biology, 2024
3. Frequency-dependent ecological interactions increase the prevalence, and shape the distribution, of preexisting drug resistance

   Jeff Maltas, Dagim Shiferaw Tadele, Arda Durmaz, Christopher D McFarland, Michael Hinczewski, and Jacob G Scott

   PRX Life, 2024
4. Cell-Cell Fusion in Cancer: The Next Cancer Hallmark?

   Paulameena V Shultes, Davis T Weaver, Dagim S. Tadele, Rowan J Barker-Clarke, and Jacob G Scott

   The International Journal of Biochemistry & Cell Biology, 2024

2023

1. Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data

   Alvaro Köhn-Luque, Even Moa Myklebust, Dagim Shiferaw Tadele, Mariaserena Giliberto, Leonard Schmiester, Jasmine Noory, Elise Harivel, Polina Arsenteva, Shannon M Mumenthaler, Fredrik Schjesvold, and 1 more author

   Cell Reports Methods, 2023
2. Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems

   Sara Hamis, Panu Somervuo, J Arvid Ågren, Dagim Shiferaw Tadele, Juha Kesseli, Jacob G Scott, Matti Nykter, Philip Gerlee, Dmitri Finkelshtein, and Otso Ovaskainen

   Journal of mathematical biology, 2023
3. Maintaining, masking, and mimicking selection: the interplay of cell-intrinsic and cell-extrinsic effects upon eco-evolutionary dynamics

   Rowan Barker-Clarke, Jason M Gray, Dagim Shiferaw Tadele, Michael Hinczewski, and Jacob G Scott

   bioRxiv, 2023
4. Early response evaluation by single cell signaling profiling in acute myeloid leukemia

   Benedicte Sjo Tislevoll, Monica Hellesøy, Oda Helen Eck Fagerholt, Stein-Erik Gullaksen, Aashish Srivastava, Even Birkeland, Dimitrios Kleftogiannis, Pilar Ayuda-Durán, Laure Piechaczyk, Dagim Shiferaw Tadele, and 1 more author

   Nature communications, 2023

2021

1. A cell competition–based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation

   Dagim Shiferaw Tadele, Joseph Robertson, Richard Crispin, Maria C Herrera, Markéta Chlubnová, Laure Piechaczyk, Pilar Ayuda-Durán, Sachin Kumar Singh, Tobias Gedde-Dahl, Yngvar Fløisand, and 1 more author

   Journal of Biological Chemistry, 2021

2017

1. Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response

   Sandra Jernström, Vesa Hongisto, Suvi-Katri Leivonen, Eldri Undlien Due, Dagim Shiferaw Tadele, Henrik Edgren, Olli Kallioniemi, Merja Perälä, Gunhild Mari Mælandsmo, and Kristine Kleivi Sahlberg

   Breast Cancer: Targets and Therapy, 2017